Isolation of Bioactive compounds from the essential oil of Jambolan (Syzygium cumini) and Invitro evaluation of biological potential

The essential oil from leaves of the Syzygium cumini is the subject of this essay, which concentrates on its chemical makeup, antioxidant properties, cytotoxicity (as measured by the mortality and hemolysis of brine shrimp) and antibacterial properties. According to the results of the GC-MS study, 39 substances were discovered. Among these, α-pinene (22.29%), (E)-ocimene (11.68%), D-limonene (7.96%) and α-terpineol (5.26%) are the most noticeable. The free radical scavenging assay (33.17 g/mL), β-carotene in linoleic acid, and percent inhibition in linoleic acid (54.9%) systems were used to test the Syzygium cumini essential oil's antioxidant activity. Oil's antibacterial activity was tested using two-gramme-negative bacteria, four-gramme-positive bacteria, and four pathogenic fungi. The most susceptible fungi and bacteria were Aspergillus niger and Streptococcus Aureus, with MIC values of 2.03 and 3.83 mg/mL, respectively. The LC50 value of the S.cumini leaf essential oil was 29.45 µg/mL for cytotoxicity against Artemia salina nauplii, and the minimum hemolytic activity was 4.26% at a dosage of 0.5 mg/mL